RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-17
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
cell counting kit-8 analysis; qPCR etc.
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Resveratrol Inhibits the TGF- beta 1-Induced Proliferation of Cardiac Fibroblasts and Collagen Secretion by Downregulating miR-17 in Rat
Year
2018
Function
This inhibitory effect of resveratrol is orchestrated by the downregulation of miR-17 and the regulation of smad7.